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4049 Interstate 49 South Service Road

4049 Interstate 49 South Service Rd, Opelousas, LA 70570, USA
Available Now
$15/SF/YR
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FOR LEASEOffice / Medical
Total Building Space
9,860SF
Lease Rate
$15/SF/YR
Zoning
C1
Gross Leasable Area
8,600SF
Maximum Contiguous
4,300SF
Minimum Divisible
4,300SF
Listing Contacts
1 / 2
Senior Advisor
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AI Property Insights
Distilled from listing data, documents and public records · 30-second read

Newly renovated 8,669 SF medical office suite at 4049 Interstate 49 South Service Road, Opelousas, Louisiana, available July 9, 2026 on a full-service gross lease at $15/month.

The move-in-ready space is designed for healthcare operations and features nine exam rooms, updated clinical finishes, multiple work areas, and extensive built-in cabinetry. The flexible layout accommodates a variety of medical and office users. Located along the I-49 South Service Road corridor in C-1 zoning, the property offers outstanding visibility, convenient interstate access, and ample on-site parking—ideal for healthcare providers seeking a modern, accessible practice location.

Lease terms are negotiable, and the property is available for direct lease.

Why it works
  • 8,669 SF move-in-ready medical office suite
  • Nine exam rooms with updated clinical finishes
  • Full-service gross lease; lease length negotiable
  • Prime I-49 corridor location with high visibility
  • Ample on-site parking
AI-generated. Verify figures, lease terms & zoning before relying on them.

More property details

Total Lease Rate
$15/SF/YR
No of Spaces/Suites
2
Tenancy
Multiple
Lease Type
Full Service Gross
Lease Rate Type
Yearly
Category
Medical
Lease Model
Direct
Lease Length
Negotiable
Available
Jul 9, 2026

Space Availability

Total: 2
Unit Name
Floor
Unit No
Size
Term
Lease Rate
Condition

About this property

This newly renovated 8,669 SF medical office suite offers a prime leasing opportunity along the I-49 South Service Road in Opelousas, providing outstanding visibility, convenient access, and direct interstate connectivity within a thriving commercial corridor. Designed for efficient healthcare operations, the move-in-ready space features nine exam rooms, updated clinical finishes, multiple work areas, extensive built-in cabinetry, and a functional, professional layout. With ample on-site parking and a flexible design suitable for a variety of medical and office users, this property is well-positioned to meet the needs of healthcare providers seeking a modern, accessible practice location.

Location

4049 Interstate 49 South Service Road

Documents

FILE
4049 Flyer.pdf
1.40 MB · Listing document
4049 Interstate 49 South Service Road
office · Opelousas · LA
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